MATERNAL AGE

It has been known for a long time that the risk of having a baby born with an extra chromosome increases with the mother's age, especially after 35 years of age. The following table gives approximate risks of chromosomal abnormalities associated with maternal age. Any concerns you have about your particular risk should be fully discussed with your doctor.

 

Mother's age at delivery

Chance of a live-born baby with Down Syndrome *

Chance of having a live-born child with any chromosomal abnormality *

20

1 in 1923

1 in 526

21

1 in 1695

1 in 526

22

1 in 1538

1 in 500

23

1 in 1408

1 in 500

24

1 in 1299

1 in 476

25

1 in 1205

1 in 476

26

1 in 1124

1 in 476

27

1 in 1053

1 in 455

28

1 in 990

1 in 435

29

1 in 935

1 in 417

30

1 in 885

1 in 384

31

1 in 826

1 in 384

32

1 in 725

1 in 322

33

1 in 592

1 in 285

34

1 in 465

1 in 243

35

1 in 365

1 in 178

36

1 in 287

1 in 149

37

1 in 225

1 in 123

38

1 in 177

1 in 105

39

1 in 139

1 in 80

40

1 in 109

1 in 63

41

1 in 85

1 in 48

42

1 in 67

1 in 39

43

1 in 53

1 in 31

44

1 in 41

1 in 24

45

1 in 32

1 in 18

46

1 in 25

1 in 15

47

1 in 20

1 in 11

48

1 in 16

1 in 8

49

1 in 12

1 in 7


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